Use of ink-jet printing to produce diffraction-based biosensors

Details Use of ink-jet printing to produce diffraction-based biosensors Use of ink-jet printing to produce diffraction-based biosensors

G - Physics

01

N

G01N 33/545 (2006.01) G01N 33/543 (2006.01) G01N 33/544 (2006.01) G01N 33/553 (2006.01)

Patent

CA 2406511

The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is ink-jet printed a specific, predetermined pattern of binder, such as an antibody. Upon attachment of a target analyte to select areas of the plastic film upon which the binder is printed, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.

L'invention concerne un dispositif sensible et peu coÛteux ainsi qu'un proc~d~ permettant de d~tecter et de quantifier des analytes pr~sents dans un milieu. Ce dispositif comprend un film m~tallis~ sur lequel est imprim~ par jet d'encre un motif pr~d~termin~ de liant, tel qu'un anticorps. Lorsqu'un analyte cible est fix~ afin de choisir les zones du film plastique sur lesquelles le liant est imprim~, une diffraction de la lumi­re transmise et/ou r~fl~chie se produit via les dimensions physiques et un placement d~fini et pr~cis de l'analyte. On obtient ainsi une image de diffraction qui peut Útre vue ~ l'oeil nu, ou ~ventuellement, au moyen d'un dispositif de d~tection.

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