Method of detecting probnp with a monoclonal antibody...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/26 (2006.01) C12N 5/20 (2006.01) G01N 33/531 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2522378

The present invention relates to antibodies binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.

La présente invention concerne des anticorps se liant spécifiquement au marqueur de l'insuffisance cardiaque proBNP natif (<= pro-brain natriuretic peptide >=), une méthode de détection spécifiquede proBNP natif, une méthode de corrélation du niveau de proBNP natif avec le diagnostic d'une insuffisance cardiaque, un kit de détection de proBNP natif et une lignée cellulaire d'hydrome produisant un anticorps contre proBNP natif.

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