C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) A61K 38/44 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2429376
The present invention relates to new genes encoding for the production of novel nox enzyme proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
La présente invention concerne des gènes codant pour la production de protéines d'enzymes nox impliquées dans la génération d'intermédiaires oxygénés réactifs affectant la division cellulaire. L'invention concerne également des vecteurs contenant ces gènes, des cellules transfectées avec ces vecteurs, des anticorps devenus actifs contre ces protéines, des nécessaires de détection, de localisation et de mesure de ces gènes et protéines, ainsi que des procédés permettant de déterminer l'activité des protéines de l'invention.
Cheng Guangjie
Lambeth J. David
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Emory University
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