Diagnosis of prostate cancer

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/30 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2597687

Methods for diagnosing prostate cancer, and differentiate prostate cancer from other prostate complications, and use of said method, and diagnosing and monitoring lymph gland metastasis, post operative examinations, and examinations during or after radiation, cytostatic, and androgen treatments are disclosed. The methods comprise injecting tracer-labelled PSA or hK2 specific antibodies, visualising PSA or hK2 producing tissue with the aid of a visualisation method, and diagnosing prostate cancer from the difference in visualisation.

L'invention concerne des méthodes de diagnostic du cancer de la prostate et de différenciation du cancer de la prostate d'autres complications se produisant au niveau de la prostate. Cette invention a aussi pour objet l'utilisation desdites méthodes, le diagnostic et la surveillance de métastase au niveau du ganglion lymphatique, des examens postopératoires et des examens effectués pendant ou après une radiothérapie, un traitement cytostatique et un traitement à l'androgène. Ces méthodes consistent à injecter un antigène spécifique de la prostate étiqueté d'un marqueur ou des anticorps spécifiques de hK2, à visualiser le tissu produisant l'antigène spécifique de la prostate ou hK2 au moyen d'une méthode de visualisation, et à diagnostiquer un cancer de la prostate à partir de la différence décelée lors de la visualisation.

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