C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 227/04 (2006.01) C07C 229/08 (2006.01)
Patent
CA 2699192
The present invention relates to a method for preparing pregabalin{(S)-3- (aminomethyl)-5-methylhexanoic acid}, which is useful for the prevention and treatment of seizure disorders, pains, and psychiatric disorders. According to the present invention, pregabalin can be prepared in a high enantiomeric excess of 99% or more, without an additional step of separating or purifying its enantiomer.
La présente invention concerne un procédé de préparation de pregabaline { acide (S) -3- (aminométhyle) -5-méthylhexanoïque}, qui convient pour la prévention et le traitement de troubles épileptiques, de douleurs et de troubles psychiatriques. Selon la présente invention, la pregabaline peut être préparée avec un excédent énantiomérique élevé de 99 % ou plus, sans étape additionnelle de séparation ou de purification de son énantiomère.
Lee Hee-Seung
Lee Joohee
Ok Taedong
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Kaist
LandOfFree
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