Retro-, inverso - and retro-inverso synthetic peptide analogues

Details Retro-, inverso - and retro-inverso synthetic peptide analogues Retro-, inverso - and retro-inverso synthetic peptide analogues

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) C07K 5/02 (2006.01) C07K 7/02 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) C07K 14/18 (2006.01) C07K 14/34 (2006.01) C07K 14/435 (2006.01) C07K 14/445 (2006.01) C07K 16/08 (2006.01) C07K 16/10 (2006.01) C07K 16/12 (2006.01) C07K 16/18 (2006.01) C07K 16/20 (2006.01) G01N 33/569 (2006.01) G01N 33/576 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2143823

Synthetic peptide antigen analogues of native peptide antigens with partial or complete retro, inverso or retro-inverso modifications are provided. When administered as an immunogen to an immunocompetent host the synthetic peptide antigen analogues induce the production of antibodies which recognise the native peptide antigen. Uses of these analogues, vaccines and methods of preparing vaccines comprising these antigen analogues, and antibodies generated using these antigen analogues are also provided.

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