Protein having zn finger-like motif

Details Protein having zn finger-like motif Protein having zn finger-like motif

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2300367

A gene encoding a novel protein having a Zn finger-like motif, which has been successfully isolated from cDNAs originating in human fetal brain by preparing primers based on an EST sequence retrieved by using the information of domains seemingly playing important functional roles in the TRAF (TNF receptor associated factor) family and employing these primers.

L'invention concerne un gène qui code une nouvelle protéine possédant un motif Zn du type doigt et que l'on a isolé avec succès à partir d'ADNc provenant d'un cerveau foetal humain en préparant des amorces basées sur une séquences EST obtenue par utilisation d'informations de domaines jouant apparemment des rôles fonctionnels importants dans la famille des TRAF (facteur associé au récepteur de TNF), et en utilisant ces amorces.

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