Method of producing concentrated non-buffered solutions of...

A - Human Necessities – 61 – K

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A61K 38/39 (2006.01) A61K 38/27 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2275193

Aqueous, non-buffered solutions containing high concentrations of fibronectin and other wound healing promoters are produced, which can then be used to make topical gel and cream formulations with high concentrations wound healing promoters. The formulations are used for the healing of cutaneous wounds. The formulations provide slow release and increased contact time of fibronectin and of other wound healing promoters to the wound site leading to the effective absorption of the promoters.

L'invention concerne la production de solutions aqueuses non tamponnées contenant des concentrations élevées de fibronectine et d'autres adjuvants de la cicatrisation, qui peuvent ensuite être utilisées pour préparer des formulations de gels et de crèmes topiques contenant des concentrations élevées d'adjuvants de la cicatrisation. Ces formulations sont utilisées pour la cicatrisation de blessures cutanées. Etant à libération lente, elles allongent le temps de contact de la fibronectine et des autres adjuvants de la cicatrisation avec le site de la blessure, ce qui permet une absorption efficace desdits adjuvants.

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