Tricyclic carbamate jak inhibitors

Details Tricyclic carbamate jak inhibitors Tricyclic carbamate jak inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/506 (2006.01) A61K 31/538 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2736258

The present disclosure relates to 2,4-pyrimidinediamines substituted with tricyclic carbamates and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, such as JAK2 or JAK3, is therapeutically useful.

La présente invention concerne des 2,4-pyrimidinediamines substituées par des carbamates tricycliques, et les compositions et procédés utilisant ces composés dans le traitement d'affections dans lesquelles la modulation de la voie JAK ou l'inhibition des kinases JAK, telles que JAK2 ou JAK3, est utile sur le plan thérapeutique.

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