C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/129, 530/13,
C12N 15/62 (2006.01) A61K 38/09 (2006.01) A61K 39/385 (2006.01) C07K 7/23 (2006.01) C07K 14/245 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 15/16 (2006.01) C12N 15/31 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2040441
This invention relates to the preparation of novel fusion proteins which comprise an analogue of LHRH and TraTp or an analogue of TraTp. The fusion proteins of the invention are useful as components of vaccines for the inhibition or control of reproductive functions in vertebrate hosts. The invention also relates to polynucleotide molecules encoding the fusion proteins, to transformant hosts expressing the fusion proteins and to methods of inhibiting or controlling reproductive function in vertebrate hosts using the fusion proteins or vaccines of the invention.
La présente invention concerne la préparation de nouvelles protéines de fusion qui comprennent un analogue de la LHRH-TraTp ou un analogue de la TraTp (protéine TraT). Les protéines de fusion de l'invention sont utiles comme constituants de vaccins pour inhiber ou contrôler les fonctions reproductrices chez des vertébrés hôtes. L'invention concerne également des molécules polynucléotidiques codant les protéines de fusion, les hôtes transformés exprimant les protéines de fusion et les méthodes pour inhiber ou contrôler les fonctions reproductrices chez des vertébrés hôtes à l'aide des protéines de fusion ou vaccins de l'invention.
Russell-Jones Gregory J.
Stewart Andrew G.
Tsonis Con G.
Bereskin & Parr
Biotechnology Australia Pty Ltd
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