Biodegradable injectable implants and related methods of...

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/02 (2006.01) A61K 9/50 (2006.01) A61K 47/30 (2006.01) A61L 27/48 (2006.01)

Patent

CA 2452412

This invention is directed to the field of medical implants, and more specifically to biodegradable injectable implants and their methods of manufacture and use. The injectable implants disclosed herein comprise glycolic acid and bio-compatible/bio-absorbable polymeric particles containing a polymer of lactic acid. The particles are small enough to be injected through a needle but large enough to avoid engulfment by macrophages. The injectables of this invention may be in a pre-activated solid form or an activated form (e.g., injectable suspension or emulsion).

L'invention concerne le domaine des implants médicaux, et plus spécifiquement des implants injectables biodégradables ainsi que leurs procédés de fabrication et d'utilisation. Ces implants injectables comprennent de l'acide glycolique et des particules polymériques, biologiquement absorbables et compatibles, contenant un polymère d'acide lactique. Ces particules sont d'une taille dont la petitesse autorise l'injection par une aiguille, mais dont la grandeur permet d'éviter l'engouffrement par les macrophages. Les implants injectables de cette invention peuvent se trouver sous une forme solide pré-activée ou sous une forme activée (par exemple, suspension ou émulsion injectable).

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