Filtering unit comprising calendered removing leukocytes layers

A - Human Necessities – 61 – M

Patent

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A61M 1/00 (2006.01) A61M 1/02 (2006.01) A61M 1/34 (2006.01) A61M 1/36 (2006.01) A61M 5/165 (2006.01) B01D 15/00 (2006.01) B01D 39/16 (2006.01)

Patent

CA 2418448

One object of the invention is a filtration unit (1) intended to allow the removal of leukocytes from a fluid such as blood or a blood component, the unit containing a porous element (5) comprising a medium (8) for the removal of leukocytes by adsorption and filtration of the leukocytes, said medium comprising a number of layers (9) of one and the same type which are formed from at least one porous non-woven material, in which at least one layer (9a) has been pressed by calendering prior to the stacking thereof, said at least one calendered layer (9a) being disposed on the downstream side of the stack, while the medium (8) comprises at least one non-calendered layer (9b). The invention also relates to a bag-based system comprising such a unit (1), said system being in particular arranged for the sterile and closed-circuit filtration of the fluid.

L'invention porte notamment sur une unité de filtration (1) conçue pour permettre d'isoler les leucocytes d'un liquide comme le sang ou un composant du sang. L'unité contient un élément poreux (5) contenant un milieu (8) destiné à l'isolement des leucocytes par adsorption et à la filtration des leucocytes. Ledit milieu comprend plusieurs couches (9) d'un seul type, lesquelles sont formées d'au moins un matériau poreux non tissé, dans lequel au moins une couche (9a) a été obtenue par calandrage avant son empilage, au moins une couche calandrée (9a) étant disposée en aval de la pile. Le milieu (8) comprend au moins une couche non calandrée (9b). L'invention porte également sur un système à base de sacs constitué de cette unité (1), ledit système étant spécialement conçu pour la filtration stérile et en circuit fermé du liquide.

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