Use of b-type natriuretic peptide as a prognostic indicator...

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2412648

The present invention relates to materials and procedures for evaluating the prognosis of patients suffering from acute coronary syndromes. In particular, the level of BNP, or a marker related to BNP, in a patient sample, alone or in combination with one or more other prognostic markers, provides prognostic information useful for predicting near-term morbidity and/or mortality across the entire spectrum of acute coronary syndromes, including unstable angina, non-ST-elevation non-Q wave myocardial infarction, ST-elevation non-Q wave MI, and transmural (Q-wave) MI.

La présente invention se rapporte à des matières et à des procédures permettant d'évaluer le pronostic de patients souffrant de syndromes coronariens aigus. En particulier, le taux du peptide natriurétique de type B (BNP), ou d'un marqueur lié au BNP, dans un prélèvement effectué chez un patient, seul ou en association à un ou plusieurs marqueurs pronostiques, fournit des informations pronostiques permettant de prédire une morbidité et/ou mortalité à court terme pour la totalité du spectre des syndromes coronariens aigus, notamment des angines de poitrine instables, des infarctus du myocarde sans ondes Q et sans sus-décalage de ST, des infarctus du myocarde sans ondes Q et avec sus-décalage de ST et des infarctus du myocarde transmuraux (à ondes Q).

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