Compositions and methods of using rna interference of...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A01H 5/00 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2676295

The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential nematode gene, which is a nematode sca1-like gene, and relates to the generation of plants that have increased resistance to parasitic nematodes.

La présente invention porte sur des compositions d'ARN double brin et des plantes transgéniques capables d'inhiber l'expression de gènes essentiels dans des nématodes parasites, et sur des procédés associés. De façon spécifique, l'invention porte sur l'utilisation de l'interférence d'ARN pour inhiber l'expression d'un gène de nématode essentiel cible, qui est un gène analogue à sca1 de nématode, et porte sur la génération de plantes présentant une résistance accrue à des nématodes parasites.

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