A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/50 (2006.01) A61J 3/07 (2006.01) A61K 9/00 (2006.01) B01J 13/04 (2006.01) B01J 13/22 (2006.01)
Patent
CA 2050689
CHEWABLE SPHEROIDAL COATED MICROCAPSULES AND METHODS FOR PREPARING SAME: ABSTRACT OF THE DISCLOSURE The present invention pertains to a chewable spheroidal coated microcapsule under about 850 microns in diameter which comprises at least one spray congealed spheroidal microcapsule core under about 200 microns in diameter, a first wax spray coating layer over the core, and a second oil coating layer over the first coated core, wherein the coated microcapsule comprises (A) microcapsule core comprising, in percentages by weight of- the microcapsule core (a) a medicament present in an amount from about 1% to about 40%, (b) an edible material having a melting point from about 25° C. to about 100° C. selected from the group consisting of (i) fatty acids having an iodine value from about 1 to about 10, (ii) natural waxes, (iii) synthetic waxes, and (iv) mixtures thereof, present in an amount from about 9.5% to about 98.5%, (c) an emulsifying agent present in an amount from about 0.5% to about 20%, (B) a first wax spray coating layer over the microcapsule core comprising, in percentages by weight of the first coating layer (a) an edible material having a melting point from about 25° C. to about 100° C. selected from the group consisting of (i) fatty acids having an iodine value from about 1 to about 10, (ii) natural waxes, (iii) synthetic waxes, and (iv) mixtures thereof, present in an amount from about 60% to about 99.5%, (b) an emulsifying agent present in an amount from about 0.5% to about 20%, and (C) a second oil coating layer over the first coated microcapsule core comprising an edible vegetable oil having a melting point in the range from about 25° C. to about 90° C.
Macrae & Co.
Tai Anna W.
Warner-Lambert Company
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