Polymorphs of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 281/02 (2006.01) A61K 31/554 (2006.01)

Patent

CA 2679936

Disclosed herein are novel polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide. Also described herein are novel pharmaceutical compositions comprising one or more 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide polymorphs, methods of making, and related methods of treatment.

L'invention concerne de nouveaux polymorphes de S,S-dioxyde d'acide 7-[(3-chloro-6,11-dihydro-6-méthyldibenzo[c,f][1,2]thiazépin-11-yl)amino]heptanoïque. Sont également décrites ici de nouvelles compositions pharmaceutiques comprenant un ou plusieurs polymorphes de S,S-dioxyde d'acide 7-[(3-chloro-6,11-dihydro-6-méthyldibenzo[c,f][1,2]thiazépin-11-yl)amino]heptanoïque, procédés de fabrication et procédés de traitement apparentés.

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