Multivalent immunogenic composition containing rsv subunit...

Details Multivalent immunogenic composition containing rsv subunit... Multivalent immunogenic composition containing rsv subunit...

A - Human Necessities

61

K

A61K 39/295 (2006.01) A61K 39/145 (2006.01) A61K 39/155 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2355270

Immunogenic compositions for administration to adults, particularly to the elderly, to protect them against disease caused by infection by respiratory syncytial virus and by influenza virus comprise an immunoeffective amount of a mixture of purified fusion (F) protein, attachment (G) protein and matrix (M) protein of RSV and an immunoeffective amount of a non-virulent influenza virus preparation. The components of the composition, when formulated as a vaccine for in vivo administration, do not impair the immunogenicity of each other. The immunogenic composition may also contain an adjuvant.

Compositions immunogènes destinées à être administrées aux adultes, notamment aux personnes âgées, afin de les protéger contre les maladies provoquées par le virus respiratoire syncytial et par l'Influenzavirus. Les compositions comprennent une quantité immunogène d'un mélange constitué de la protéine de fusion (F), de la protéine de fixation (G) et de la protéine de matrice (M) du RSV purifiées et d'une quantité immunogène d'une préparation d'Influenzavirus non virulent. Les différents composants de la composition, formulés sous forme de vaccin destiné à l'administration in vivo, n'interfèrent pas entre eux pour ce qui est de l'antigénicité. Les compositions immunogènes peuvent contenir en outre un adjuvant.

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