Use of heteroaryl substituted n-(indole-2-carbonyl-) amides...

A - Human Necessities – 61 – K

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A61K 31/404 (2006.01) A61K 31/422 (2006.01) A61K 31/427 (2006.01) A61K 31/454 (2006.01) A61K 31/4709 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/53 (2006.01) A61K 31/5355 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01)

Patent

CA 2339676

Disclosed is a pharmaceutical composition containing a glycogen phosphorylase inhibitor of Formula I or IA as defined herein to treat infection in a mammal; (see formula I, IA) wherein the dotted line is an optional bond; A is an optionally substituted C atom; R1, R8 and R9 are each H or substituent such as halo; R2 is H; R3 is H or alkyl; R4 is H or optionally substituted alkyl; R5 is H, OH, alkyl or the like; R6 is -COR10 in which R10 is heterocycle; R7 is H, F or alkyl; R12 is H or optionally substituted alkyl; R13 is H or optionally substituted alkyl; and R14 is heterocycle.

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