Systems and methods for producing asynchronous neural...

A - Human Necessities – 61 – N

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A61N 1/34 (2006.01)

Patent

CA 2750570

Systems and methods for producing asyn-chronous neural responses to treat pain and/or other pa-tient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequen-cy, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with indi-vidual neurons of the sensory neural population complet-ing corresponding individual refractory periods at differ-ent times, resulting in an asynchronous sensory neuron response to the electrical signal.

L'invention porte sur des systèmes et des procédés de génération de réponses neurales asynchrones pour le traitement de la douleur et/ou d'autres états de santé chez un patient. Un procédé selon un mode de réalisation particulier comprend la sélection d'une fréquence de stimulation cible supérieure à une fréquence de seuil, la fréquence de seuil correspondant à une période réfractaire pour les neurones d'une population cible de neurones sensoriels. Le procédé peut en outre comprendre la génération chez le patient d'une sensation de paresthésie par application d'un signal électrique à de multiples neurones sensoriels de la population cible de neurones sensoriels à la fréquence de simulation, avec des neurones individuels de la population de neurones sensoriels achevant des périodes réfractaires individuelles correspondant à différentes durées, conduisant à une réponse asynchrone des neurones sensoriels au signal électrique.

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