C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C07K 16/00 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2168349
A method for conducting gene therapy is provided. The therapy involves using a recombinant gene that encodes an antibody that birds an antigen associated with a disease. The invention is in particular useful in providing cells with "immunity" against intracellular pathogens. Novel vectors and cell lines also are provided.
L'invention concerne un procédé de réalisation d'une thérapie génique. La thérapie consiste à utiliser un gène de recombinaison qui code un anticorps se liant à un antigène associé à une maladie. L'invention est notamment utilisée dans la production de cellules ayant une "immunité" contre des agents pathogènes intracellulaires. L'invention se rapporte également à de nouveaux vecteurs et lignées cellulaires.
Duan Lingxun
Pomerantz Roger
Borden Ladner Gervais Llp
Thomas Jefferson University
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