A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/18 (2006.01) A61K 31/216 (2006.01) A61K 31/255 (2006.01) A61K 31/343 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2335062
This invention is the coadministration of ACAT and MMP inhibitors for the reduction of both the macrophage and smooth muscle cell component of atherosclerotic lesions, thus impairing the expansion of existing lesions and the development of new lesions and for the prevention of plaque rupture and the promotion of lesion regression in a mammal.
La présente invention concerne la co-administration d'inhibiteurs de ACAT et de métalloprotéinase matricielle (MMP) pour la réduction à la fois de la composante macrophages et de la composante cellules musculaires lisses des lésions athéroscléreuses, ce qui empêche l'extension de lésions existantes et l'apparition de nouvelles lésions, tout en prévenant la rupture des plaques d'athérome et en favorisant la régression des lésions chez un mammifère.
Macrae & Co.
Warner-Lambert Company Llc
LandOfFree
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