Hybrid transforming growth factors

Details Hybrid transforming growth factors Hybrid transforming growth factors

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/495 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2082450

Abstract of the disclosure Novel hybrid Transforming Growth Factors The invention relates to novel hybrid TGF-Bs, a process for the production of biologically active, dimeric hybrid proteins and pharmaceutical compositions comprising them. Hybrid TGF-Bs produced by this process can be used in various therapeutic modalities such as for the promotion and acceleration of wound healing and bone and tissue repair, the treatment of cancer, as a bone marrow protective agent, mediator of cardioprotection, antiinflammatory or immunosuppressive agent or as a growth regulator in mammalian cell cultures.

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