4-amino...

Details 4-amino... 4-amino...

C - Chemistry, Metallurgy

07

D

C07D 215/42 (2006.01) A61K 31/47 (2006.01) C07D 215/46 (2006.01) C07D 221/16 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2344248

Cholesteryl ester transfer protein inhibitors, of the Formula (I), prodrug thereof, or a pharmaceutically acceptable salt of said compound or of said prodrug, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

L'invention porte sur des inhibiteurs de la protéine de transfert d'ester de cholestéryle (CETP) de la formule (I), sur un promédicament de celle-ci ou sur un sel pharmaceutiquement acceptable de ce composé ou du promédicament, sur des compositions pharmaceutiques contenant ces inhibiteurs et sur leur utilisation pour rehausser certains taux de lipides du plasma tels que le cholestérol à lipoprotéines de haute densité et pour réduire certains autres taux de lipides du plasma tels que le LDL cholestérol et les triglycérides et, en conséquence, pour traiter des maladies qui sont aggravées par des taux faibles de HDL cholestérol et/ou par des taux élevés de LDL cholestérol et de triglycérides telles que l'athérosclérose et les maladies cardio-vasculaires, chez certains mammifères, y compris l'homme.

Affiliated with

Also associated with

Rating

4-amino... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-amino..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-amino... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1549416