Genes

Details Genes Genes

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2493675

We described primordial germ cell expressed genes, Fragilis and Stella. The sequences and uses of human Stella and Fragilis are disclosed, as well as several related mouse sequences related to Fragilis. Stella and Fragilis which are markers for primordial germ cells and may be used to identify such cells in cell populations. They may also be used for diagnosing, treating and/or preventing diseases such as cancers.

L'invention concerne deux gènes exprimés spécifiquement dans des cellules germinales embryonnaires, Fragilis et Stella. Les séquences et utilisations de Stella et Fragilis sont décrites, ainsi que plusieurs séquences de souris apparentées à Fragilis. L'invention porte sur Stella et Fragilis qui sont des marqueurs pour les cellules germinales embryonnaires et qui peuvent être utilisés pour l'identification desdites cellules dans des populations cellulaires. Ils peuvent également être utilisés pour le diagnostic, le traitement et/ou la prévention de maladies telles que les cancers.

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