New substituted imidazo-pyridinones and...

Details New substituted imidazo-pyridinones and... New substituted imidazo-pyridinones and...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61P 5/48 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2508233

The invention relates to substituted imidazo-pyridinones and imidazo- pyridazinones of general formula (I) wherein R1 - R4 are defined as in Claim, the tautomers thereof, the stereoisomers thereof, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, especially an inhibitory effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP- IV).

Imidazo-pyridinones et imidazo-pyridazinones substituées de formule générale (I) dans laquelle R?1¿ à R?4¿ sont tels que définis dans la revendication 1, leurs tautomères, leurs stéréoisomères, leurs mélanges et leurs sels, qui possèdent des propriétés pharmacologiques précieuses, en particulier un effet inhibiteur de l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).

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