C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/07 (2006.01) A61K 31/18 (2006.01) A61K 31/38 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07C 311/14 (2006.01) C07C 311/32 (2006.01) C07D 215/42 (2006.01) C07D 335/06 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2227930
Compounds of the formula I (see fig. I) in which R(1) to R(8) and X have the meanings indicated in the claims, are useful for the production of medicaments having K+channel-blocking action; in particular for the production of a medicament for the treatment or prophylaxis of stimulated gastric acid secretion; of ulcers of the stomach and of the intestinal region; of reflux esophagitis; of diarrhea; of all types of arrhythmias, including ventricular and supraventricular arrhythmias; and of reentry arrhythmias and for the prophylaxis of sudden heart death as a result of ventricular fibrillation.
Brendel Joachim
Gerlach Uwe
Lang Hans Jochen
Weidmann Klaus
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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