Process for preparing 63 - carboxyamides of teicoplanin...

Details Process for preparing 63 - carboxyamides of teicoplanin... Process for preparing 63 - carboxyamides of teicoplanin...

C - Chemistry, Metallurgy

07

K

530/9, 167/103.6

C07K 9/00 (2006.01) A61K 38/14 (2006.01) C07K 1/107 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2003325

ABSTRACT The present invention is directed to an improved process for preparing 63 carboxyamides of teicoplanin (eventually having 15-N-alkyl substituents) by reacting a teicoplanin like compound with an activated ester forming reagent to give an ester function which is substituted by an amine, by contacting an excess of said amine in an organic polar solvent at a temperature comprised between 5°C and 60°C.

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