Anti-tsg101 antibodies and their uses for treatment of viral...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/70 (2006.01) C07K 16/00 (2006.01) C07K 16/10 (2006.01)

Patent

CA 2500596

The present invention provides methods of using antibodies that bind a TSG101 protein to inhibit or reduce viral production. The invention also provides methods of using the TSG101 antibodies for the treatment of viral infections, including HIV infection. The invention further provides methods of detecting viral infected cells using TSG101 antibodies.

L'invention concerne des méthodes d'utilisation d'anticorps se fixant à la protéine TSG101 afin d'inhiber ou de limiter la production virale. Elle concerne également des méthodes d'utilisation de ces anticorps anti-TSG101 pour le traitement d'infections virales, y compris l'infection par VIH. Elle concerne, de plus, des méthodes servant à détecter des cellules atteintes d'infections virales au moyen de ces anticorps anti-TSG101.

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