5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the...

Details 5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the... 5-heterocyclyl pyrazolo[4,3-d]pyrimidin-7-ones for the...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 15/10 (2006.01)

Patent

CA 2342830

The invention is directed to novel substituted 5-heterocyclyl pyrazolopyrimidinones and derivatives thereof, their synthesis and their use in treating sexual dysfunction in mammals, especially male erectile dysfunction. Pharmaceutical compositions containing the compounds and methods of using them to treat sexual dysfunction are also described.

Cette invention se rapporte à de nouvelles pyrazolopyrimidinones 5-hétérocyclyle substituées et à des dérivés de celles-ci, à leur synthèse et à leur utilisation dans le traitement de certaines dysfonctions sexuelles chez les mammifères notamment les troubles de l'érection chez l'homme. Des compositions pharmaceutiques contenant ces composés et des procédés d'utilisation de ces compositions pour traiter certaines dysfonctions sexuelles sont également présentés.

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