Process for the preparation of...

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C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01)

Patent

CA 2568652

The invention relates to a process for preparing mixtures of enantiomers of PPI~s proton pump inhibitors having a sulphinyl structure, i.e. Pyridine-2- ylmethylsulfinyl-1H-benzimidazoles, using a mixture of enantiomers of chiral zirconium complexes or chiral hafnium complexes.

L'invention concerne un procédé permettant de préparer des mélanges d'énantiomères d'inhibiteurs de la pompe à protons (IPP), présentant une structure sufinyle, à savoir des Pyridin-2-yl-méthy-lsulfinyl-1H-benzimidazoles, à partir d'un mélange d'énantiomères de complexes chiraux de zirconium ou de complexes chiraux de hafnium.

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