Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2442729

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention a pour objet des séquences d'acide nucléique qui codent des polypeptides liées au récepteur couplé à la protéine G. L'invention concerne aussi des polypeptides codés par ces séquences d'acide nucléique, et des anticorps qui se lient de manière immunospécifique aux polypeptides, ainsi que des dérivés, des variants, des mutants, ou des fragments des polypeptides, polynucléotides ou anticorps susmentionnés. Cette invention porte aussi sur des méthodes de thérapie, de diagnostic et de recherche pour diagnostiquer, traiter et prévenir des troubles impliquant n'importe lesquels de ces acides nucléiques humains et protéines humaines.

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