Regulated gene expression in yeast

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/19 (2006.01) C12N 15/63 (2006.01) C12N 15/66 (2006.01) C12N 15/67 (2006.01) C12N 15/81 (2006.01)

Patent

CA 2301888

The invention provides novel yeast cells comprising genes whose expression can be modulated by growth in the presence or absence of metal ions, methods for making such yeast cells, and methods of using such yeast cells for determining the requirement for expression of particular genes of the growth or viability of the yeast cells.

L'invention se rapporte à de nouvelles cellules de levure comportant des gènes dont l'expression peut être modulée selon que la culture de levure s'effectue en présence ou en l'absence d'ions métalliques. Elle se rapporte également à des techniques de fabrication de telles cellules de levure et à des techniques d'utilisation de ces cellules de levure permettant d'évaluer la nécessité d'expression de gènes particuliers pour assurer la croissance ou la viabilité des cellules de levure.

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