Tia-1 binding proteins and isolated complementary dna...

Details Tia-1 binding proteins and isolated complementary dna... Tia-1 binding proteins and isolated complementary dna...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2151261

Complementary DNA (cDNA) has been isolated having a sequence that encodes a polypeptide that binds TIA-1 in a double transformation. In one embodiment, the polypeptide is immunologically reactive with the monoclonal antibody produced by the hybridoma designated ATCC #HB-11721. Specific cDNA sequences have been determined and amino acid sequences have been deduced therefrom.

De l'ADN complémentaire (ADNc) comprenant une séquence codant un polypeptide fixant TIA-1 dans une transformation double a été isolé. Dans un mode de réalisation, le polypeptide réagit immunologiquement avec l'anticorps monoclonal produit par l'hybridome enregistré sous la référence ATCC #HB-11721. Des séquences d'ADNc spécifiques ont été déterminées et des séquences d'acides aminés en ont été déduites.

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