Technetium-99m labeled peptides for thrombus imaging

Details Technetium-99m labeled peptides for thrombus imaging Technetium-99m labeled peptides for thrombus imaging

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 51/08 (2006.01) C07K 4/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2136330

This invention relates to radiolabeled reagents that are scintigraphic imaging agents for imaging sites of thrombus forma- tion in vivo, and methods for producing such reagents. Specifically, the invention relates to reagents each comprised of a specific binding compound, capable of binding to at least one component of a thrombus, covalently linked to a radiolabel-binding moie- ty. The invention provides these reagents, methods and kits for making such reagents; and methods for using such reagents lab- eled with technetium-99m to image thrombus sites in a mammalian body,

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