Multi-mer peptides derived from hepatitis c virus envelope...

Details Multi-mer peptides derived from hepatitis c virus envelope... Multi-mer peptides derived from hepatitis c virus envelope...

C - Chemistry, Metallurgy

07

K

C07K 14/18 (2006.01) A61K 39/29 (2006.01) C12N 15/51 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2305847

Multimer peptides (e.g. 30- to 45-mer peptides) derived from hepatitis C virus envelope proteins reacting with the majority of anti-HCV antibodies present in patient sera are described. The usage of the latter peptides to diagnose, and to vaccinate against, an infection with hepatitis C virus is also disclosed.

La présente invention concerne des peptides multimères (par exemple, 30 à 45 peptides monomères) dérivés de protéines d'enveloppe de virus d'hépatite C réagissant avec la majorité des anticorps anti-HCV présents chez un patient. La présente invention concerne également l'utilisation de ces peptides pour diagnostiquer une infection à virus d'hépatite C ou pour vacciner contre celle-ci.

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