Anti-il-20 antibodies and binding partners and methods of...

Details Anti-il-20 antibodies and binding partners and methods of... Anti-il-20 antibodies and binding partners and methods of...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2519057

The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-20 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. The present invention includes anti-IL-20 and anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-20 using such antibodies and binding partners.

La présente invention concerne le blocage, l'inhibition, la réduction, la production d'un effet antagoniste ou la neutralisation de l'activité de molécules du polypeptide IL-20. IL-20 et IL-22 sont des cytokines qui sont impliquées dans des processus inflammatoires et des maladies chez l'homme. La présente invention concerne des anticorps anti-IL-20 et anti-IL-22RA et leurs partenaires de liaison, ainsi que des méthodes de production d'un effet antagoniste dirigé contre IL-20 au moyen de ces anticorps et de leurs partenaires de liaison.

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