Hla class i and ii binding peptides and their uses

Details Hla class i and ii binding peptides and their uses Hla class i and ii binding peptides and their uses

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/04 (2006.01) A61K 39/385 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2425648

The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.

L'invention concerne des moyens et des procédés destinés à sélectionner des peptides immunogènes et des compositions de peptides immunogènes capables de lier de manière spécifique des glycoprotéines codées par des allèles HLA et à induire l'activation de lymphocytes T restreints par un allèle. Les peptides sont utiles dans l'élicitation d'une réponse immunitaire contre un antigène souhaité.

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