C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/273 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) C07C 271/22 (2006.01) C07D 205/085 (2006.01) C07D 207/14 (2006.01) C07D 207/416 (2006.01) C07D 211/76 (2006.01) C07D 223/10 (2006.01) C07D 223/12 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2223403
The compounds of formula (I) exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More especially, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula (I), compositions containing compounds of formula (I), and their use, which are for treating a patient suffering from, or subject to, physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.
Les composés de formule (I) présentent une utilité pharmacologique et, de ce fait, on les incorpore dans des compositions pharmaceutiques et on les utilise dans le traitement de patients souffrant de certains troubles médicaux. Ils sont, plus particulièrement, des inhibiteurs de l'activité du Facteur Xa. L'invention concerne des composés de formule (I), des compositions contenant lesdits composés, ainsi que leur utilisation dans le traitement de patients souffrant d'états physiologiques, ou sujets à ces états, qu'on peut améliorer par administration d'un inhibiteur de l'activité du Facteur Xa.
Becker Michael R.
Cheney Daniel L.
Choi-Sledeski Yong Mi
Ewing William R.
Mason Jonathan Stephen
Aventis Pharmaceuticals Inc.
Goudreau Gage Dubuc
Rhone-Poulenc Rorer Pharmaceuticals Inc.
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