Genes and proteins for the biosynthesis of lactimidomycin

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/52 (2006.01) C07K 14/36 (2006.01) C07K 16/12 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/16 (2006.01) C12N 15/31 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12N 15/55 (2006.01) C12P 17/18 (2006.01) C12P 19/62 (2006.01) C12P 21/02 (2006.01) G06F 17/30 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2453675

Genes and proteins involved in the biosynthesis of polyketides by microorganisms, including the genes and proteins forming the biosynthetic loci for the polyketide dorrigocin from Streptomyces platensis subsp. rosaceus and the polyketide lactimidomycin from Streptomyces amphibiosporus. The genes and proteins allow direct manipulation of dorrigocin, lactimidomycin and related chemical structures via chemical engineering of the enzymes involved in the biosynthesis of dorrigocin and lactimidomycin.

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