Heterocyclic compounds for inhibition of gastric acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2311798

The present invention relates to heterocyclic compounds of formula (I), in which the phenyl moiety is substituted with lower alkyl in 2- and 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.

La présente invention concerne des composés hétérocycliques représentés par la formule (I), dans laquelle la fraction phényle est substituée par alkyle inférieur en position 2 et 6. Ces composés inhibent la sécrétion d'acide gastrique stimulée par voie exogène ou endogène, et peuvent par conséquent servir dans la prévention et le traitement de maladies inflammatoires gastro-intestinales.

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