Taste masking system for non-plasticizing drugs

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/14 (2006.01)

Patent

CA 2593016

The present invention relates to taste masking system, taste masked formulations, dosage forms made from those formulations and methods of making those formulations that involve dissolving or dispersing a pH dependant polymer and a non-plasticizing active pharmaceutical ingredient in a solvent, granulating using that material or forming layers over a solid support therewith. This can be followed with the use of a taste masking overcoating layer.

L'invention concerne un système de masquage de goût, des formulations à goût masqué, des formes posologiques constituées de ces formulations et des méthodes de fabrication de ces formulations, ces méthode consistant à dissoudre ou à disperser un polymère dépendant du pH et un ingrédient pharmaceutique actif non plastifiant dans un solvant, à former des granulés au moyen de ce matériau ou à former des couches sur un support solide à l'aide de ce matériau. On peut ensuite utiliser une couche de revêtement masquant le goût.

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