Combinations of penicillanic acid 1,1-dioxide with...

Details Combinations of penicillanic acid 1,1-dioxide with... Combinations of penicillanic acid 1,1-dioxide with...

A - Human Necessities

61

K

167/187

A61K 31/545 (2006.01) A61K 31/425 (2006.01) A61K 31/43 (2006.01) C07D 499/00 (2006.01)

Patent

CA 1132046

ABSTRACT OF THE DISCLOSURE Penicillanic acid 1,1-dioxide, pharmaceutically-acceptable salts thereof, and esters thereof readily hydrolyzable in vivo, enhance the anti- bacterial effectiveness of 7-(D-2-[4-ethylpiperazin-2,3-dione-1-carboxamido]- 2-[4-hydroxyphenyl]acetamido)-3-([1-methyl-5-tetrazolyl]thiomethyl)-3- desacetoxymethylcephalosporanic acid, and salts thereof, against many beta- lactamase producing bacteria.

331436

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