Interface assembly for pre-concentrating analytes in...

G - Physics – 01 – N

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G01N 30/12 (2006.01)

Patent

CA 2522276

A system for interfacing a sampling device and a chromatograph and for pre- concentrating analytes in a sample prior to introducing the sample into the chromatographic column is generally disclosed comprising an interface housing with a first channel and an adsorbent housing with a second channel, which contains at least one adsorbent. Valveless conduits permit fluid to be communicated between the sampling device and the first channel, between the first channel and the second channel, and the first channel and the column. In some embodiments, fluid flows in one direction when the analytes are adsorbed and in the opposite direction when analytes are desorbed. In certain embodiments, two different adsorbents are disposed in the second channel to adsorb different types of analytes.

Cette invention concerne d'une manière générale un système permettant d'interfacer un dispositif d'échantillonnage et un chromatographe et de préconcentrer des analytes dans un échantillon avant l'introduction de l'échantillon dans la colonne chromatographique, lequel système comprend un boîtier d'interface doté d'un premier canal et un boîtier d'adsorbant doté d'un deuxième canal et contenant au moins un adsorbant. Des conduits dépourvus de soupape permettent à un fluide de circuler entre le dispositif d'échantillonnage et le premier canal, entre le premier canal et le deuxième canal et entre le premier canal et la colonne. Dans certains modes de réalisation, le fluide s'écoule dans un sens lorsque les analytes sont adsorbés et s'écoule dans le sens opposé lorsque les analytes sont désorbés. Dans certains modes de réalisation, deux adsorbants différents sont introduits dans le deuxième canal afin qu'ils adsorbent différents types d'analytes.

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