Stable chewing gum compositions comprising maltitol and...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/465 (2006.01)

Patent

CA 2699806

Use of a nicotine-cellulose combination, maltitol and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine.

La présente invention concerne l'utilisation d'un complexe nicotine-cellulose, de maltitol et d'une gomme de base pour la préparation d'une composition de chewing-gum permettant à un sujet de ressentir rapidement l'effet de la nicotine après avoir commencé à mâcher la composition de chewing-gum. La composition de chewing-gum est, de préférence, préparée par compression directe et elle ne se désintègre pas lors de sa mastication. L'invention concerne également des compositions de chewing-gum comprenant de la nicotine, lesdites compositions assurant une libération rapide de ladite nicotine.

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