G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/564 (2006.01) C07K 16/18 (2006.01) G01N 33/576 (2006.01)
Patent
CA 2223642
The invention is directed to methods and kits for detecting and measuring the presence or absence of perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis or type 1 autoimmune hepatitis. The methods and kits of the present invention provide safe and reliable means for diagnosing ulcerative colitis, primary sclerosing cholangitis, and type 1 autoimmune hepatitis. The antigens reactive with perinuclear anti-neutrophil cytoplasmic autoantibody of ulcerative colitis and primary sclerosing cholangitis are also provided.
L'invention se rapporte à des méthodes et à des trousses permettant de détecter et de mesurer la présence ou l'absence des anticorps cytoplasmiques périnucléaires anti-neutrophiles de la rectocolite hémorragique, de l'angiocholite sclérosante primitive ou de l'hépatite auto-immune de type 1. Les méthodes et les trousses de la présente invention constituent des moyens sûrs et fiables de diagnostiquer la rectocolite hémorragique, l'angiocholite sclérosante primitive et l'hépatite auto-immune de type 1. L'invention concerne également les antigènes réagissant avec les auto-anticorps cytoplasmiques périnucléaires anti-neutrophiles de la rectocolite hémorragique et de l'angiocholite sclérosante primitive.
Targan Stephan R.
Vidrich Alda
Cedars-Sinai Medical Center
Gowling Lafleur Henderson Llp
LandOfFree
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