C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 11/00 (2006.01) C07K 14/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12P 21/04 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2395811
The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
La présente invention concerne de nouvelles protéines, notamment des molécules d'acide nucléique isolées codant de nouveaux polypeptides. Elle concerne de nouveaux polypeptides, et des anticorps qui se lient à ces polypeptides. L'invention concerne également des vecteurs, des cellules hôtes, et des méthodes recombinantes et synthétiques de production de polynucléotides et/ou de polypeptides humains et des anticorps. Elle concerne des méthodes diagnostiques et thérapeutiques servant à diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles liés à ces nouveaux polypeptides. Elle concerne en outre des méthodes de criblage permettant d'identifier des agonistes et des antagonistes des polynucléotides et polypeptides de l'invention. L'invention concerne enfin des méthodes et/ou des compositions pouvant inhiber ou améliorer la production et la fonction des polypeptides de l'invention.
Barash Steven C.
Rosen Craig A.
Ruben Steven M.
Barash Steven C.
Human Genome Sciences Inc.
Mbm & Co.
Rosen Craig A.
Ruben Steven M.
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