Diagnosis of vascular disease susceptibility using...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/12 (2006.01) A61K 31/7088 (2006.01) A61K 39/118 (2006.01) A61K 48/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2447823

Methods are provided for determining susceptibility of a patient to vascular disease according to presence of chlamydia infected with bacteriophage .PHI.Cpn1, and compositions for use in such methods. The compositions include bacteriophage .PHI.Cpn1 proteins and nucleic acids, elementary bodies from chlamydia infected with .PHI.Cpn1, and antibodies thereto.

La présente invention concerne des méthodes qui permettent de déterminer la vulnérabilité d'un patient aux maladies vasculaires en fonction de la présence de chlamydia infectée par le bactériophage FCpn1, et des compositions destinées à être utilisées dans de telles méthodes. Les compositions comprennent des protéines de bactériophage FCpn1 et des acides nucléiques, des corps élémentaires provenant de chlamydia infectée par FCpn1, et des anticorps correspondants.

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