Substituted n-benzoyl-n'-(2-phenylethyl)-piperazines

Details Substituted n-benzoyl-n'-(2-phenylethyl)-piperazines Substituted n-benzoyl-n'-(2-phenylethyl)-piperazines

C - Chemistry, Metallurgy

07

D

C07D 295/16 (2006.01) A61K 31/495 (2006.01) C07D 295/192 (2006.01)

Patent

CA 2056874

4-18447/A Substituted N-benzoyl-N'-(2-phenylethyl)-piperazines Abstract N-Benzoyl-N'-(2-phenylethyl)-piperazines of formula I Image (I), wherein R1, R2, R3, R4 and R5 have the meanings as defined in the specification, and salts thereof, have analgesic properties and can be used as analgesic active ingredients in medicaments. They are prepared, for example, as follows: a compound of formula II Image (II), wherein X1 is carboxy or reactive functionally modified carboxy, or a salt thereof, is reacted with a compound of formula III Image (III), wherein X2 is hydrogen.

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