Novel carbamoyloxy aryl alkan arylpiperazine compound,...

Details Novel carbamoyloxy aryl alkan arylpiperazine compound,... Novel carbamoyloxy aryl alkan arylpiperazine compound,...

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) C07D 241/04 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2686547

There is provided a novel carbamoyloxy arylalkan arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Ibrmula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain (i.e., acute or chronic pain, neuropathic pain, inflammatory pain, diabetic pain, postherpetic neuralgia, etc.), anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.

L'invention concerne un nouveau composé dérivé de carbamoyloxy arylalcane arylpipérazine possédant de nombreuses caractéristiques racémiques ou énantiomères, représenté par la formule générale 1, ainsi que ses sels et ses hydrates de qualité pharmaceutique. L'invention concerne également une composition pharmaceutique destinée au traitement de la douleur (la douleur aigüe ou chronique, la douleur neuropathique, la douleur inflammatoire, la douleur due au diabète, la névralgie postherpétique, etc.), de l'anxiété ou de la dépression, comprenant une dose utile du composé, ainsi qu'une méthode de traitement de la douleur, de l'anxiété ou de la dépression chez les mammifères, comprenant l'administration d'une dose utile du composé aux mammifères nécessitant un tel traitement.

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