Polypeptides that bind baff and/or april

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 47/48 (2006.01) A61P 37/02 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C12N 15/12 (2006.01) C12N 15/28 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2585927

The present invention relates to novel polypeptides and TACI variants that bind APRIL, novel polypeptides and TACI variants that bind BAFF, nucleic acid molecules encoding the polypeptides, host cells comprising the nucleic acid molecules, compositions comprising the polypeptides or nucleic acid molecules, and methods of using the polypeptides and nucleic acid molecules.

L'invention concerne de nouveaux polypeptides et des variants de TACI qui se lient avec APRIL, de nouveaux polypeptides et des variants de TACI qui se lient avec BAFF, de molécules d'acide nucléique codant pour ces polypeptides, des cellules hôtes comprenant ces molécules d'acide nucléique, des compositions contenant ces polypeptides ou ces molécules d'acide nucléique, et des méthodes d'utilisation de ces polypeptides et molécules d'acide nucléique.

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